Queen Mary

Insecticidal toxins from black widow spider venom

Insecticidal toxins from black widow spider venom: Toxicon 49, 531-549 (2007)

Figure 2


Fig. 2. The 3D structures of a-LTX and d-LIT monomers. Comparison of the side and top views of the alpha-LTX monomer obtained by single-particle analysis of cryo-electron micrographs (Orlova et al., 2000) with similar views of the d-LIT monomer, reconstructed by single-particle analysis of negative-stain electron micrographs. The domains of alpha-LTX are marked as in (Orlova et al., 2000); tentative domain assignments in the delta-LIT reconstruction are based on the interactive overlap of the 3D maps, fitting of ARs and volumetric analysis. Both volumes were low-pass filtered to 20A. (J. Nield, R. Abbondati, B. Odier, A. Rohou, Y. Ushkaryov, unpublished results).

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© Toxicon, 2007